Using Charles Darwin's four premises of hypothesis of natural selection, how does an antibiotic resistant strain of bacteria develop when a naturally occurring population of bacteria is exposed to an antibiotic?

According to Charles Darwin theory, the variations are raw materals for the selection of fittest among them. The bacteria, which are suitable to cope with the antibiotics effects, are selected by nature. Thank you

An antibiotic-resistant strain of bacteria develops when a naturally occurring population of bacteria is exposed to an antibiotic through the following mechanisms:

1. Variation: Within the bacterial population, there is genetic variation, including mutations that may confer resistance to the antibiotic.

2. Inheritance: Bacteria with advantageous mutations that confer resistance to the antibiotic are more likely to survive and reproduce, passing on their resistance genes to future generations.

3. Competition: The presence of the antibiotic creates a selective pressure, favoring the survival and reproduction of bacteria with resistance genes over those without, leading to an increase in the frequency of the resistant strain within the population.

4. Differential survival and reproduction: Bacteria with resistance genes have a higher chance of surviving and reproducing in the presence of the antibiotic, leading to the proliferation of the antibiotic-resistant strain within the population over time.