What is the role of cytoskeleton during apoptosis?

The cytoskeleton's primary function in apoptosis is to cause the cell to shrink and round during the process as a result of enzymes breaking down the cytoskeleton. Actin and keratins are two other cytoskeleton proteins that are involved in controlling apoptotic signaling.

The cytoskeleton is involved in the regular morphological changes that occur during apoptosis, such as cell shrinkage and membrane blebbing. It also helps to maintain the shape and structural integrity of the cell. As apoptosis advances, the cytoskeleton reorganizes, which results in the disintegration of cellular structures and the final fragmentation of the cell into apoptotic bodies. Finally, the cytoskeleton facilitates the movement of organelles and cellular components during apoptosis, which guarantees the orderly dismantling of the cell.