How is glycolysis related to the citric acid cycle?

Answer 1

Glycolysis produces the starting material for the Tricarboxylic Acid Cycle.

In every stage of glycolysis, two pyruvates are produced from one glucose molecule.

Pyruvate dehydrogenase is a massive enzyme complex that connects glycolysis and the Tricarboxylic Acid Cycle.

It produces acetyl-Coenzyme A (acetyl-CoA) from pyruvate.

#underbrace("CH"_3"COCOO"^(-))_color(red)("pyruvate") + "HSCoA" + "NAD"^+ stackrel("pyruvate dehydrogenase")(→) underbrace("CH"_3"CO-SCoA")_color(red)("acetyl-CoA") + "CO"_2 + "NADH"#

The Tricarboxylic Acid Cycle's starting material is acetyl-Coenzyme A.

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Answer 2

Madeline Andrews

Pyruvate enters the citric acid cycle, where it is further oxidized to produce more NADH and FADH2, as well as ATP through substrate-level phosphorylation. The citric acid cycle also generates precursor molecules for other biosynthetic pathways. Glycolysis is the first metabolic pathway that breaks down glucose into pyruvate, producing ATP and NADH.

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Answer from HIX Tutor

When evaluating a one-sided limit, you need to be careful when a quantity is approaching zero since its sign is different depending on which way it is approaching zero from. Let us look at some examples.