Hydration via Hydroboration-Oxidation

Hydration via hydroboration-oxidation is a chemical process utilized in organic synthesis to introduce hydroxyl (-OH) groups into unsaturated organic compounds. This method involves the addition of water across carbon-carbon double bonds in the presence of borane (BH3) and an oxidizing agent, typically hydrogen peroxide (H2O2). The reaction proceeds through a concerted mechanism, offering regioselective and stereoselective control over the hydration of alkenes and alkynes. This approach has garnered significant attention due to its efficiency in producing valuable functional groups with high synthetic utility, particularly in pharmaceutical and fine chemical industries.