Protein sequence comparisons
Protein sequence comparison is a fundamental method in bioinformatics, essential for understanding the evolutionary relationships and functional similarities between proteins. By analyzing the amino acid sequences of proteins, scientists can elucidate their structural and functional characteristics, aiding in the prediction of protein function, identifying homologous proteins across species, and uncovering evolutionary patterns. Through algorithms such as BLAST (Basic Local Alignment Search Tool) and multiple sequence alignment techniques, researchers can identify conserved regions, domains, and motifs within protein sequences, providing valuable insights into their roles in biological processes. Protein sequence comparison is integral to numerous fields, including drug discovery, evolutionary biology, and molecular biology.
- Why can comparisons of protein similarity between species can reveal the degree of genetic kinship?
- If a protein common to two different species has many amino acid differences, what can be concluded?
- Why is protein sequencing useful?
- What is the function of RNA in protein sequencing?
- What are some examples of protein sequence comparisons?
- BLAST is a computational tool used by genome biologists to do what?
- What do biochemical similarities tell us about evolution?
- How might studying DNA help scientists piece together the history of life on Earth?
- Which of the following may decide characteristic of protein? A) Number of amino acids in the protein B) Number of disulphide bonds in the protein C) Number of polypeptide chains in the protein D) Sequence of amino acids in the protein
- The nucleotide sequence of one DNA strand of a DNA double helix is 5-ʹGGATTATTGTGCACTTTCA-3ʹ. What is the sequence of the complementary strand and briefly explain the answer?