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What kinds of proteins make up the mitotic spindle?

Answer 1

Mitotic spindle is mainly made of microtubules. These microtubules are made by polymerisation of globular tubulin proteins.

There are three types of microtubules in a spindle apparatus.

In interpolar microtubules, polymerisation of tubulin takes place near equatorial region of spindle apparatus while tubulin subunits are lost near polar regions.
Chromosomes of a dividing cell get attached to kinetochore microtubules.
In the polar region of apparatus, there are astral microtubules.

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Kinesin molecules help in elongation of interpolar microtubules during anaphase, while dynein molecules help in poleward migration of sister chromatids (hence in chromatid separation during anaphase).

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Answer 2

Ivy Acosta

Microtubules and associated proteins, such as kinesins and dyneins, comprise the mitotic spindle.

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Answer from HIX Tutor

When evaluating a one-sided limit, you need to be careful when a quantity is approaching zero since its sign is different depending on which way it is approaching zero from. Let us look at some examples.