What chemicals are responsible for the adverse effects ofaspirin?

Question

Mateo Aguilar · Accepted Answer

Well, aspirin is a single chemical, i.e. #1,2-C_6H_4(CO_2H)(OC(=O)CH_3)#

And its ease of synthesis, and its wide range of action, makes this one of the most useful pharmaceuticals known.

AS with any drug, the dose determines the poison (Paracelsus recognized this in the 16th century!). And so a regular dose of aspirin of even #0.100-0.500*g# might be benign, and beneficial. Exceed these doses, and certainly you will cause tissue damage and even death by overdose.

Cooper Adams · Answer

undefined The adverse effects of aspirin are primarily attributed to its active ingredient, acetylsalicylic acid. This compound can irritate the stomach lining, leading to gastrointestinal issues such as ulcers, bleeding, and discomfort. Additionally, aspirin can interfere with the blood's clotting mechanism, which may result in increased risk of bleeding, particularly in individuals who are predisposed to bleeding disorders or are taking anticoagulant medications. In rare cases, aspirin may also trigger allergic reactions or respiratory problems, such as asthma exacerbations.