If a cell loses or ejects its nucleus, what is its fate and why?

A cell's nucleus houses its DNA, which contains all the information needed for the cell to remain alive and divide when necessary. Without the nucleus, the cell cannot make the proteins and enzymes necessary for self-sustenance, and it cannot divide.

It's interesting to note that for certain body cells, the ejection of the nucleus (enucleation or denucleation) is a normal process and doesn't always indicate that the cell isn't functioning. This applies to:

It wouldn't be advantageous for other cells, which is why researchers are investigating the possibility of using this process of (d)enucleation to treat cancer. Cancer cells are able to divide uncontrollably, but they would be unable to do so in the absence of a nucleus.

If a cell loses or ejects its nucleus, its fate is typically cell death because the nucleus contains the cell's genetic material (DNA), which is essential for cellular functions such as protein synthesis and replication. Without the nucleus, the cell cannot perform vital processes necessary for survival.