How many Good's buffer agents exist?

Question

Caleb Adams · Accepted Answer

There are 20 Good buffers.

Named after Norman Good, they are all physiological buffers with #"p"K_a# values ranging from 6.1 to 8.5. The buffers, with their #"p"K_a# values, are: MES: #"2-("N"-morpholino)ethanesulfonic acid"#, 6.15 ADA: #N"-(2-acetamido)iminodiacetic acid"#, 6.62 PIPES: #"piperazine-"N,N′"-bis(2-ethanesulfonic acid)"#, 6.82 ACES: #N"-(2-acetamido)-2-aminoethanesulfonic acid"#, 6.88 MOPSO: #"3-("N"-morpholinyl)-2-hydroxypropanesulfonic acid"#, 6.95 Cholamine chloride: #("CH"_3)_3 stackrel(+)("N")"CH"_2"CH"_2"NH"_2, "Cl"^"-"#, 7.10 BES: #N,N"-bis(2-hydroxyethyl)-2-aminoethanesulfonic acid"#, 7.17 MOPS: #"3-("N"-morpholino)propanesulfonic acid"#, 7.20 TES: #N"-[tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid"#, 7.40 HEPES: #"4-(2-hydroxyethyl)-1-piperazinylethanesulfonic acid"#, 7.48 DIPSO: #N,N"-bis(2-hydroxyethyl)-3-amino-2-hydroxypropanesulfonic acid"#, 7.60 TAPSO:# "3-["N"-tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid"#, 7.60 Acetamidoglycine: #"CH"_3"CONHNHCH"_2"COOH"#, 7.7 POPSO: #"piperazine-"N,N′"-bis(2-hydroxypropanesulfonic acid)"#, 7.85 HEPPSO: #"4-(2-hydroxyethyl)piperazine-1-(2-hydroxypropanesulfonic acid)"#, 7.85 HEPPS: #"3-[4-(2-hydroxyethyl)-1-piperazinyl]propanesulfonic acid"#, 8.00 Tricine: #N"-[tris(hydroxymethyl)methyl)]glycine"#, 8.15 Glycinamide: #"NH"_2"CH"_2"CONH"_2#, 8.20 Bicine: #N,N"-bis(2-hydroxyethyl)glycine"#, 8.35 TAPS: #N"-tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid"#, 8.44

Henry Antrim · Answer

undefined There are twelve Good's buffer agents, each with different pKa values, allowing for buffering within various pH ranges.