How is pyruvate converted to acetyl coA?

Answer 1

Pyruvate is converted into Acetyl CoA in an intermediate process just before the Citric Acid Cycle.

Here it reacts with Coenzyme A. Here it loses two of it's oxygens and one of it's carbons to form Carbon Dioxide. Also, one molecule of NAD+ is reduced to form NADH. The resulting molecule is a molecule of Acetyl CoA.

This diagram I drew should help sum everything up:

In addition, here's a video that explains this, in case you like it better that way:

Video (By Scott Collins)

Hope that helped :)

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Answer 2

Penelope Adams

Pyruvate decarboxylation, which takes place in the mitochondria, is the process by which pyruvate loses a carbon dioxide molecule and joins forces with coenzyme A to form acetyl CoA. The enzyme pyruvate dehydrogenase complex catalyzes this reaction, which calls for multiple cofactors, including lipoic acid, thiamine pyrophosphate, and coenzyme A.

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Answer from HIX Tutor

When evaluating a one-sided limit, you need to be careful when a quantity is approaching zero since its sign is different depending on which way it is approaching zero from. Let us look at some examples.