How can disruption of the cell cycle result in cancer?

Question

Piper Anderson · Accepted Answer

Cell cycle continues in a highly regulated manner: when the regulation is disrupted, the cycle progresses in an uncontrolled way resulting in cancer.

Cancer is called a malignant neoplasm. Neoplasm is a newly grown abnormal mass of tissue. Malignancy is a condition when cells continue to divide despite overcrowding which a normal cell will never do.

There are several check points in cell cycle when a cell may recognise damage and thus may proceed to disintegrate itself which is termed apoptosis. All such capabilities of a normal cell are lost in the malignant one.

Sebastian Alvarado · Answer

undefined Disruption of the cell cycle can result in cancer by allowing cells to divide uncontrollably, leading to the formation of tumors. This disruption can occur due to mutations in genes that regulate the cell cycle, such as tumor suppressor genes or oncogenes.