Home > Organic Chemistry > Quick Introduction of Structures

How are peptide bond formed?

Answer 1

Through condensation reactions, where water is released and one amino acid bonds to another.

Amino acids have the basic structure of #NH_2CHCOOHR#, where #R# is a side-chain that varies between one amino acid and another.

They look like this:

When peptide bonds form, between one amino acid and another, the hydroxyl (#-OH#) group of the carboxylic acid and one hydrogen (#-H#) of the amino group fall off, and other amino acids bonds to them.

Carboxylic acid groups bond to amino groups, and vice versa.

The hydroxyl group and hydrogen combine to form water (#H_2O#), which is why this is called a condensation reaction.

An amino acid polymer or polypeptide looks like this:

By signing up, you agree to our Terms of Service and Privacy Policy

Answer 2

Addison Armstrong

Peptide bonds are formed through a dehydration synthesis reaction between the carboxyl group of one amino acid and the amino group of another. This process results in the release of a water molecule and the formation of a covalent bond between the carbon and nitrogen atoms of the respective groups.

By signing up, you agree to our Terms of Service and Privacy Policy

Answer from HIX Tutor

When evaluating a one-sided limit, you need to be careful when a quantity is approaching zero since its sign is different depending on which way it is approaching zero from. Let us look at some examples.