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Does alcohol react with the Grignard reagents?

Answer 1

Absolutely: alcohol is a protic solvent.

#R-MgX + DO-R' rarr R-D + R'O-MgX#

The reaction represents the reaction of a Grignard reagent. #R-MgX#, with deuterio-alchohol, #R'O""^2H#; this is a way of introducing a deuterium label into an alkyl chain. I would have got the same organic product had I reacted the Grignard with #D_2O#.

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Answer 2

Elias Aguila

No, alcohol does not react with Grignard reagents. Grignard reagents typically react with compounds containing acidic protons, such as ketones, aldehydes, esters, and carbon dioxide.

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Answer from HIX Tutor

When evaluating a one-sided limit, you need to be careful when a quantity is approaching zero since its sign is different depending on which way it is approaching zero from. Let us look at some examples.