A solution of Rocephin 285mg/mL does not freeze.what can be the explanation?

Question

Henry Antrim · Accepted Answer

#"Freezing point depression"# is a so-called colligative property....

And such properties, which depend on the number of solute species in solution, tend to (i) INCREASE the boiling point of the solution with respect to the pure solvent; and (ii) DECREASE the freezing point of the solution with respect to the pure solvent. And so if you gots an aqueous solution....the freezing point should be a trifle less than #0# #""^@C#, and its boiling point should be a trifle more than #100# #""^@C#. Of course I have assumed an aqueous solution, and both #"freezing point depression"#, and #"boiling point elevation"# will be proportional to the concentration of #"rocephin"#, whatever this is..... So the solute has REDUCED the melting point so that the freezer is insufficiently cold to freeze the solution.

Avery Adams · Answer

undefined The likely explanation for a solution of Rocephin 285mg/mL not freezing is that it contains an additive or solute that lowers its freezing point. This phenomenon is known as freezing point depression. Rocephin, also known as ceftriaxone, is an antibiotic commonly administered intravenously or intramuscularly. Pharmaceutical formulations of Rocephin may include additives such as solvents, stabilizers, or preservatives to enhance its stability, solubility, or shelf life. These additives can lower the freezing point of the solution, preventing it from solidifying at typical freezing temperatures. Additionally, the concentration of solute in the solution may also contribute to the lowering of the freezing point. Therefore, a solution of Rocephin 285mg/mL may have additives or a high enough solute concentration to cause freezing point depression and inhibit the solution from freezing at standard freezing temperatures.