What are the products when glycine, β-alanine, γ-aminobutyric acid are heated?

Question

Nolan Allen · Accepted Answer

Here's what I get.

An important principle is that if two atoms are in a 1,5- or a 1,6-relationship to each other and can react, they will almost certainly do so.

This is because

the two groups can easily come close to each other during normal bond rotations within the molecule and
the new 5- or 6-membered ring is almost strain-free
Glycine (α-aminoacetic acid)

Thus, when glycine is heated to about 260 °C, it condenses to form the stable 6-membered ring structure of piperazine-2,5-dione.

β-alanine (β-aminopropionic acid)

β-Alanine cannot easily form a 5- or 6-membered ring.

Instead, it loses a molecule of ammonia when heated to 200 °C and forms a stable α,β-unsaturated carboxylic acid.

γ-Aminobutyric acid

γ-Aminobutyric acid is easily dehydrated to form a stable 5-membered lactam.

Easton Jones · Answer

undefined When glycine, β-alanine, and γ-aminobutyric acid are heated, they undergo thermal decomposition reactions, leading to the formation of various products. These products include water, carbon dioxide, ammonia, and other compounds depending on the specific conditions of the heating process.

Jacob Anderson · Answer

undefined When glycine, β-alanine, and γ-aminobutyric acid are heated, they undergo thermal decomposition reactions. The specific products formed depend on the exact conditions of the heating process, including temperature, pressure, and presence of any catalysts or other substances. Generally, the decomposition of these amino acids can lead to the formation of various products, including water, carbon dioxide, ammonia, and other organic compounds. Additionally, the exact decomposition pathways and products may vary for each amino acid.